Fig. 7
From: Advanced smart biomaterials and constructs for hard tissue engineering and regeneration

Smart composite to shift species in biofilms towards a healthy composition. Three-species biofilms (S. mutans, S. sanguinis and S. gordonii) were grown on composites for 48 and 72 h. The commercial composite was Heliomolar (Ivoclar). The DMAHDM wt% was varied in the experimental composite from 0 to 3%. The cariogenic S. mutans had overwhelming proportions for the commercial control and 0% DMAHDM group. With increasing DMAHDM wt%, the proportion of S. mutans sharply decreased, whereas S. sanguinis or S. gordonii achieved a predominant proportion. Values with dissimilar letters are significantly different (P < 0.05). (Adapted from ref. 146, with permission.)