Fig. 7: Minimal changes of bone dynamic histomorphometry parameters in ovariectomized Δ130–136 transgenic mice compared with wild-type (WT) and R76W groups.
From: Connexin 43 hemichannels protect bone loss during estrogen deficiency
Mice were injected twice with calcein and alizarin dyes, and plastic sections were prepared. Trabecular (a–c) and cortical (d–f) MAR, BFR/BS, and MS/BS were measured in unstained sections from the tibial mid-diaphysis. Representative images were shown in g. Scale bar = 100 μm. Data shown are mean ± SEM. *P < 0.05; **P < 0.01. n = 4. MAR, mineral apposition rate; BFR, bone formation rate; BS, bone surface; MS, mineralizing surface
