Fig. 1 | Bone Research

Fig. 1

From: Conditional disruption of the osterix gene in chondrocytes during early postnatal growth impairs secondary ossification in the mouse tibial epiphysis

Fig. 1

Conditional inactivation of osterix in epiphyseal chondrocytes reduces trabecular bone mass in the epiphyses in mice. a Representative µCT images of the tibial epiphyses of WT mice (Osxflox/flox; Cre-ERT2− treated with tamoxifen) and Osx cKO mice (Osxflox/flox; Cre-ERT2+ treated with tamoxifen) (N = 7, 4 males and 3 females). b–g Quantitative µCT data of the trabecular bone volume to total volume (Tb. BV/TV), trabecular number (Tb. N), trabecular thickness (Tb. Th), trabecular separation (Tb. Sp), bone mineral density, and connectivity density of the tibial epiphyses as shown in a. Values are the mean ± SEM (N = 5, 3 males and 2 females). (A) Significant difference (P < 0.05) in Osx cKO epiphyses as compared with WT controls

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