Fig. 2 | Bone Research

Fig. 2

From: Conditional disruption of the osterix gene in chondrocytes during early postnatal growth impairs secondary ossification in the mouse tibial epiphysis

Fig. 2

Conditional inactivation of osterix in epiphyseal chondrocytes reduces trabecular separation in the growth plate in mice. a Representative µCT images of the tibial growth plate of WT mice (Osxflox/flox; Cre-ERT2+ treated with corn oil) and Osx cKO mice (Osxflox/flox; Cre-ERT2+ treated with tamoxifen). b–g Quantitative µCT data of the trabecular bone volume to total volume (Tb. BV/TV), trabecular number (Tb. N), trabecular thickness (Tb. Th), trabecular separation (Tb. Sp), bone mineral density, and connectivity density of the tibial epiphyses as shown in a. Values are the mean ± SEM (N = 7, 4 males and 3 females). (A) Significant difference (P < 0.05) in Osx cKO epiphyses as compared with WT controls

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