Fig. 1 | Bone Research

Fig. 1

From: Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs

Fig. 1

Injection of dermal fibroblasts (DFbs) into degenerative IVDs maintains disc height. The rat IDD model was established by caudal puncture of the IVD space using 20G needles without or with DFb injection treatment for 1, 2 or 3 months. a, b Radiographic images and disc height index (DHI), c, d 3D micro-CT reconstructions and endplate BV/TV measurements, and e, f MRI and disc degenerative degree (high signal ratio in disc) 1, 2, or 3 months after surgery and treatment were acquired and measured. Error bars represent the S.D., and significant differences were assessed with Student’s t-test; *P < 0.05

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