Fig. 3 | Bone Research

Fig. 3

From: Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs

Fig. 3

IVD fibrosis after percutaneous endoscopic lumbar discectomy (PELD). a T2-weighted STIR MRI of IVDs before and after PELD in patients with L3/4 disc herniation; L3, third lumbar vertebra; L4, fourth lumbar vertebra. b, c Disc height index (DHI) and degeneration Pfirrmann score for preoperative and post-PELD patients. Values represent the mean of seven IVDs from seven patients. d Representative SOFG-stained IVD images from normal and post-PELD patients. e Nucleus pulposus ratio (orange positive staining ratio) measured from SOFG-stained IVD images. Scale bars, 500 μm. Error bars the represent S.D., and significant differences were assessed with Student’s t-test, *P < 0.05, and ****P < 0.000 1

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