Fig. 5 | Bone Research

Fig. 5

From: Epo/EpoR signaling in osteoprogenitor cells is essential for bone homeostasis and Epo-induced bone loss

Fig. 5

Mice deficient in EpoR in osteoblasts are partially protected from Epo-induced bone loss. Micro-CT analysis of the fourth lumbar vertebra of 10-week-old female cKO and WT littermates that were treated with Epo pumps (10 U) for 4 weeks. a Bone volume/total volume (BV/TV) ratio, b trabecular number (Tb.N), c trabecular thickness (Tb.Th), and d trabecular separation (Tb.Sp). Each dot indicates an individual mouse. The horizontal line represents the mean. N = 4–11 per group. *P < 0.05, **P < 0.01

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