Fig. 5 | Bone Research

Fig. 5

From: Quality control methods in musculoskeletal tissue engineering: from imaging to biosensors

Fig. 5

Summary of Raman spectroscopy techniques: polarized Raman spectroscopy (PRS), suitable for highly oriented systems; Raman microscopy, able to couple chemical and morphological information; spatially offset Raman spectroscopy (SORS), used for collecting Raman signal from deep regions; coherent Raman spectroscopy (SRS & CARS), able to improve Raman signal intensity up to 105 factor; and surface enhanced Raman spectroscopy, (SERS) able to enhance signal intensity up to 1010 factor, exploiting the plasmonic effect between the sample and metal particles. The processing of Raman data collected from biological samples is accomplished by spectral analysis and statistical treatments

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