Fig. 6

FZD9 is dispensable for the osteoanabolic action of Wnt1. a Representative contact X-rays of 6-week-old female Col1a1tTA/pTetWnt1/Fzd9+/+ or Col1a1tTA/pTetWnt1/Fzd9−/− mice, in which Wnt1 expression was silenced (Dox+) or activated by doxycycline removal for 1 week (Dox−). b Representative undecalcified spine and tibia sections from the same mice after von Kossa/van Gieson staining. c Trabecular bone mass, as determined by undecalcified histology of the spine and tibia. Data were analyzed by two-way ANOVA with Sidak’s multiple comparison test (*P < 0.05, **P < 0.01, ***P < 0.001). Error bars indicate standard deviation