Table 1 (-)-Epicatechin increases bone growth in vivo

From: Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia

 

Naso-anal length/mm

Femur length/mm

Tibia length/mm

Humerus length/mm

Radius length/mm

Ulna length/mm

Vehicle

38.51

5.27

5.26

4.98

3.93

5.11

(-)-Epicatechin

40.40

5.64

5.57

5.14

4.13

5.38

Δ Increase

+1.89 mm

+0.37 mm

+0.31 mm

+0.16 mm

+0.20 mm

+0.27 mm

Percentage of increase

+4.91%

+7.02%

+5.89%

+3.21%

+5.09%

+5.28%

P value

0.011

9.10−10

2.10−6

8.10−4

7.10−5

9.10−4

Significance

*

****

****

****

****

****

  1. The percent growth gains of the naso-anal, femur, tibia, humerus, ulna, and radius lengths with detailed values for (-)-epicatechin-injected Fgfr3Y367C/+ animals. Data are presented as the mean
  2. ns Not significant
  3. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.000 1 by two-tailed, unpaired t test
Back to article page