Fig. 3
From: Prospects and challenges of dynamic DNA nanostructures in biomedical applications
Dynamic DNA structures based on strand displacement reactions. a Schematic illustration of dynamic DNA structures based on the strand displacement reaction. b The gel electrophoresis and c fluorescence characterization results of the HCR products induced by a DSAP using DSAP-c-b to simulate target recognition. Lane M: DNA marker. d Fluorescence confocal microscopy images of target SMMC-7721 cells after incubation with different DNA probes. (i) DSAP-a + Cy5-H1-BHQ2 + H2, (ii) DSAP-a + DSAP-T3-b + Cy5-H1-BHQ2, and (iii) DSAP-a + DSAP-T3-b + Cy5-H1-BHQ2 + H2. Cells were stained with Hoechst 33342 before imaging. (Scale bar: 20 μm).89 Copyright 2020, American Chemical Society
