Fig. 5
From: Prospects and challenges of dynamic DNA nanostructures in biomedical applications
Assembly of nuclear pore complex mimics by DNA origami. a Schematic illustration of the fabrication of the DNA origami NPC mimic and its application in programmable protein arrangement. b As reported by Qi et al.34 two central channel nucleoporins of yeast origin, Nsp1 and Nup100, were expressed with a SNAP tag, which enables their conjugation with a benzylguanine-modified DNA oligo. c Illustration and TEM images of different protein-gated DNA origami NPC mimics. Scale bar = 50 nm. Copyright 2021, American Chemical Society
