Fig. 1

Adipoq-Cre-targeted cell population in bone marrow and bone. a Representative confocal images of bone marrow and trabecular bone from 1-, 4- and 9-month-old Adq-mTmG mice. GFP labeling was restricted to a small number of stromal cells at 1 month of age (arrow), while at 4 and 9 months it highlighted numerous marrow stromal (arrow) and perivascular (double arrow) cells, the majority of osteoblasts (arrowhead) and osteocytes (hollow arrowhead). b Representative fluorescent images of GFP-labelled intracortical perivascular cells (double arrow) in 4- and 9-month-old mice. bm Bone marrow, bt Bone trabecula, cb Cortical bone. Scale bars 25 μm