Fig. 5 | Bone Research

Fig. 5

From: Skeletal phenotypes in secreted frizzled-related protein 4 gene knockout mice mimic skeletal architectural abnormalities in subjects with Pyle’s disease from SFRP4 mutations

Fig. 5

Effects of Sfpr4 KO and zoledronic acid (ZA) treatment on trabecular bone parameters. Mice were dosed intraperitoneally with saline or zoledronic acid (20 μg·kg−1) at 8 weeks of age. Male and female mice were examined at 68 and 24 weeks of age, respectively. Data are means ± SEM for 5 to 8 mice per group with statistical analysis by two-factor ANOVA

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