Table 2 Association between serum ferritin levels and the prevalence of hand OA

From: Combining single-cell RNA sequencing and population-based studies reveals hand osteoarthritis-associated chondrocyte subpopulations and pathways

Items

Quintiles of serum ferritin /(μg·L−1)

P-for-trend

Q1

Q2

Q3

Q4

Q5

Hand (n)a

495

496

491

494

487

 

Median of serum ferritin levels/(μg·L−1)

75.0

138.5

213.0

308.0

564.0

 

Number of hand OA/%

99 (20.0)

105 (21.2)

104 (21.2)

119 (24.1)

136 (27.9)

 

Crude OR (95% CI)

1.00 (Ref)

1.07 (0.74–1.56)

1.07 (0.74–1.56)

1.27 (0.88–1.84)

1.55 (1.08–2.22)

0.037

Age-sex-BMI adjusted OR (95% CI)

1.00 (Ref)

1.31 (0.89–1.93)

1.23 (0.83–1.83)

1.46 (0.97–2.22)

1.69 (1.13–2.52)

0.005

  1. OA osteoarthritis, Q quantile, n number, OR odds ratio, CI confidence interval, BMI body mass index, Ref reference
  2. aThe association between serum ferritin levels and hand osteoarthritis was evaluated by a logistic regression model using generalized estimating equations (hand-specific analysis)