Fig. 1
From: The pathogenic mechanism of syndactyly type V identified in a Hoxd13Q50R knock-in mice
The establishment of Hoxd13Q50R knock-in mice. a Schematic illustration of mutation knock-in using the TALEN system. b No.10, 18, 19, and 21 of first-generation mice were confirmed to carry a heterozygous mutation of Hoxd13Q50R by NdeI digestion. (M = DNA marker, N = naïve mice). c Sanger-sequencing result of wild-type (WT/WT), Hoxd13Q50R heterozygous mice (Q50R/WT), and Hoxd13Q50R homozygous mice (Q50R/Q50R)
