Fig. 2
From: Bone loss with aging is independent of gut microbiome in mice

The presence of gut microbiome is not required for age-related trabecular bone loss. Trabecular bone volume fraction (Tb. BV/TV), cortical thickness (Ct. Th), cortical area (Ct. Ar), serum P1NP and CTX-1 of GF and colonized mice in both (a–e) female and (f–j) male mice are shown. k Representative 3D images of femur trabecular bone are shown. Data are represented as mean ± SEM. Unpaired t test or Mann-Whitney U Test was performed. ns, not statistically significant. For female, GF, n = 5; Col, n = 10. For male GF, n = 6; Col, n = 6. 2 data in (d) and (e) were missing due to insufficient sample collection