Fig. 12
From: Photothermal sensitive nanocomposite hydrogel for infectious bone defects

Histological analysis of bone repair at 4 weeks and 8 weeks post-implantation. a HE-stained sections at the respective time points. (scale bar = 100 μm). b Masson-stained sections, with an emphasis on collagen distribution (scale bar = 100 μm). c Immunohistochemical staining for CD31. The presence of CD31, indicative of endothelial cells within the tissue, is denoted by brown staining. Key annotations include HB (host bone), RB (repaired bone), H (GNAG hydrogel), and F (collagen fiber) (scale bar = 25 μm). d The quantitative positive areas of Masson-stained sections. e The quantitative of positive areas of CD31 immunohistochemical staining. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.000 1. Two-way ANOVA (n = 3)