Table 1 Criteria used for a diagnosis of PVL. In order to make the diagnosis of PVL, it was suggested that one of the two following combinations of the criteria were met: 1) three major criteria (E among them) or 2) two major criteria (E among them) + two minor criteria⁵

A

Leukoplakia lesion with more than two different oral sites, which is most frequently found in the gingiva, alveolar processes and palate

An OL lesion that occupies at least 3 cm when adding all the affected areas

B

The existence of a verrucous area

That the patient be female

C

That the lesions have spread or engrossed during development of the disease

That the patient (male or female) be a non-smoker

D

That there has been a recurrence in a previously treated area

A disease evolution higher than five years

E

Histopathologically, there can be from simple epithelial hyperkeratosis to verrucous hyperplasia, verrucous carcinoma or oral squamous cell carcinoma, whether in situ or infiltrating