Table 1 Pulp and periapical diagnosis based on the American Association of Endodontists classification with associated management options25,26

From: Symptomatic irreversible pulpitis and other orofacial pain: overcoming challenges in diagnosis and management

Diagnosis

Descriptor

Symptoms

Signs/further investigations

Management options

Pulp diagnosis

‘Normal' pulp

A clinically ‘healthy' pulp

No spontaneous pain or sensitivity reported

Under cold stimulus, pulp usually responds but pain lasts only 1-2 seconds

Other sensibility testing is positive with no lingering pain

No treatment indicated

Reversible pulpitis

Inflammation of the pulp which should resolve following removal of cause (eg caries)

No spontaneous pain

Discomfort from cold/sweet but pain lasts ≤2 seconds

Familiar pain following application of cold but resolution in 1-2 seconds

No tenderness to percussion and no radiographic changes apically

Remove cause (eg management of caries, sealing exposed dentine).

Review to ensure resolution of symptoms and maintenance of vitality

Symptomatic irreversible pulpitis

A vital inflamed pulp incapable of healing*

Sharp pain on stimulation, lasting >30 seconds (later stages may result in heat stimulus being more severe than cold)

Referred pain, may be poorly located

Spontaneous pain, sometimes exacerbated by postural change

Pain relieving medication use and loss of sleep is frequently reported

Familiar pain lasting >30 seconds following thermal stimulation

Usually positive to EPT testing (may have reduced threshold)

Pain to percussion in some cases

Apical radiographic changes are possible

Partial or complete pulpotomy followed by vital pulp treatment or root canal treatment

Pulpectomy followed by root canal treatment

Extraction

Asymptomatic irreversible pulpitis

A vital inflamed pulp incapable of healing*

No symptoms reported

Extremely deep caries and a radiograph which is likely to result in significant bacterial ingress to the pulp and therefore require pulp management

Partial or complete pulpotomy followed by vital pulp treatment or root canal treatment

Pulpectomy followed by root canal treatment

Extraction

Pulp necrosis

A necrotic pulp

No pulp symptoms reported but may have associated apical symptoms and diagnosis

Non-responsive to sensibility testing

May have associated apical signs and diagnosis

Pulpectomy followed by root canal treatment

Extraction

Previously treated

Previous endodontic treatment

No pulp symptoms reported but may have associated apical symptoms and diagnosis in the case of post-treatment disease

Non-responsive to sensibility testing

May have associated apical signs and diagnosis in the case of post-treatment disease

No treatment

Endodontic re-treatment

Extraction

Previously initiated therapy

Endodontic treatment commenced (eg pulpotomy or pulpectomy)

Depending on the stage of treatment, symptoms may include those of symptomatic irreversible pulpitis or pulp necrosis

Depending on the stage of treatment, signs may include those of symptomatic irreversible pulpitis or pulp necrosis

Root canal treatment

Extraction

Apical diagnosis

‘Normal' apical tissues

No inflammatory or infective process

Any symptoms present are likely to be pulpal origin only

No sensitivity to percussion

Normal lamina dura radiographically with normal PDL space

No treatment

If pulpal symptoms, management aligning to this

Symptomatic apical periodontitis

Periapical inflammation secondary to pulpitis or infection of the root canal system

Patients may report pain on biting of short duration

Pain is well-located

Spontaneous pain is possible

Tooth usually tender to percussion

Periapical radiolucency or hypoattenuation may be seen on radiographs/CBCT scans

Vital pulp treatment

Extirpation and root canal treatment

Endodontic re-treatment

Extraction

Asymptomatic apical periodontitis

Periapical inflammation secondary to pulpitis or infection of the root canal system

No additional symptoms to pulp diagnosis

May be asymptomatic (eg previously treated, pulp necrosis)

Tooth not tender to percussion

Periapical radiolucency or hypoattenuation may be seen on radiographs/CBCT scans

Vital pulp treatment

Extirpation and root canal treatment

Endodontic re-treatment

Extraction

Chronic apical abscess

Usually gradual onset, pus is produced in response to intra and/or extra radicular infection. Sinus is present

Usually asymptomatic

Patients may be aware of sinus/bad taste

Non vital/previously treated tooth

Presence of a sinus adjacent to tooth

Tooth mobility possible

Periapical radiolucency or hypoattenuation may be seen on radiographs/CBCT scans which is well defined and may be corticated

Root resorption is possible in long standing cases

Extirpation and root canal treatment

Endodontic re-treatment

Extraction

Acute apical abscess

Pus is produced in response to intra and/or extra radicular infection. May be exacerbation of chronic condition (eg chronic abscess, granuloma, cyst) or acute aetiology

No pain to thermal stimuli

Usually well-located pain which is spontaneous and is exacerbated by pressure

Non-vital/previously treated tooth

Tooth mobility is possible

Swelling

May be pus discharge from socket/sinus

Extirpation and root canal treatment

Endodontic re-treatment

Extraction

Antibiotics if drainage not possible and/or systemic involvement

Condensing osteitis

A localised bony reaction to low-grade long-standing inflammation

May be present secondary to other diagnosis, with symptoms aligning to this

When present in isolation, often asymptomatic

May be present secondary to other diagnosis, with signs aligning to this

Periapical radiograph shows radiopacity around root apices

Extirpation and root canal treatment

Endodontic re-treatment

Extraction.

Key:

* = Irreversibly inflamed pulp tissue may be confined to part of the pulp, the remainder being amenable to vital pulp treatments

EPT = electric pulp test

PDL = periodontal ligament

CBCT = cone-beam computed tomography