Table 1 Sample storage time and parameters tested in the study
Parameter | Sample storage time | P value | ||||||
|---|---|---|---|---|---|---|---|---|
All patient (n = 30) | ≤12 mo (n = 6) | >12 & ≤60 mo (n = 14) | > 60 mo (n = 10) | ≤12 mo vs >12 & ≤60 mo | ≤12 mo vs >60 mo | >12 & ≤60 mo vs >60 mo | ||
2D imaging | ||||||||
2D LYVE-1 density, mean (%) | 16.4 ± 1.1 | 15.7 ± 2.6 | 15.2 ± 1.1 | 18.6 ± 2.4 | 0.621 | 0.588 | 0.349 | |
3D imaging | ||||||||
3D LYVE-1 density, mean (%) | 14.4 ± 2.7 | 11.1 ± 2.2 | 12.1 ± 1.1 | 19.9 ± 7.8 | 0.602 | 0.263 | 0.412 | |
Lymphatic vessel length, mean (μm) | 60.4 ± 0.8 | 60.2 ± 2.1 | 60.2 ± 0.9 | 60.9 ± 1.6 | 0.621 | 0.562 | 0.639 | |
Lymphatic vessel radius, mean (μm) | 3.8 ± 0.1 | 3.8 ± 0.2 | 3.8 ± 0.1 | 3.9 ± 0.2 | 0.934 | 0.958 | 0.558 | |
LYVE-1 density kurtosis, mean | 3.7 ± 0.9 | 3.5 ± 1.5 | 5.1 ± 1.5 | 1.9 ± 1.2 | 0.621 | 0.313 | 0.069 | |
LYVE-1 density skewness, mean | 0.8 ± 0.2 | 0.3 ± 0.4 | 1.1 ± 0.4 | 0.6 ± 0.3 | 0.138 | 0.368 | 0.412 | |
LYVE-1 density variancea10−4, mean | 5.0 ± 0.9 | 3.7 ± 0.9 | 6.9 ± 1.8 | 3.0 ± 0.9 | 0.458 | 0.428 | 0.079 | |
