Fig. 1

SEPT9 and SHOX2 DNA methylation levels in colorectal cancer and normal tissue. SEPT9 (a) and SHOX2 (b) methylation levels in primary colorectal tumours (n = 395) and normal solid tissue (n = 45). Each rhombus reflects one sample measurement. Median values are given (black bars). P-values refer to Mann–Whitney U test. Receiver Operating Characteristic (ROC) of SEPT9 and SHOX2 methylation for the discrimination between colorectal cancer and normal tissues (c)