Fig. 1

High WSB1 expression is associated with decreased distant metastasis-free survival (DMFS) in HR-negative breast cancer patients. a WSB-1 copy number was measured by absolute qPCR in non-cancer primary breast cell line HMEpC and several breast cancer cell lines. n = 3 b WSB1 transcript levels were analysed in tissue cDNA microarrays. Dot plots represent samples arranged as normal (n = 16) and tumour (n = 128). c Kaplan–Meier (KM) plots represent DMFS according to WSB1 expression in the following cohorts: all patients (n = 1609), ER+ (n = 122), ER− (n = 170), PR+ (n = 122), and PR− (n = 95). Patients were grouped as having ‘High’ (grey) or ‘Low’ (Black) WSB1 expression, and median expression used as cut-off. HR hazard ratio *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001