Table 2 Demographic and clinical characteristics (mean [SD], % [n]) of testing groups, with some characteristics also broken down by test results
From: Psychological impact of providing women with personalised 10-year breast cancer risk estimates
Test groups | Test statistics | P values | |||
|---|---|---|---|---|---|
T-C plus SNPs | T-C only | Comparison | |||
n = 271 | n = 197 | n = 297 | |||
Age: mean (SD) | 61.94 (6.91) | 54.27 (4.19) | 52.40 (2.91) | F (2762) = 281.8 | P < 0.001 |
Moderate risk | 62.24 (6.41) | 55.10 (5.39) | 52.90 (3.60) | ||
Average risk | 61.43 (7.73) | 53.73 (3.06) | 51.91 (2.42) | ||
Below average risk | 62.04 (6.75) | 53.88 (3.44) | 52.39 (2.51) | ||
BMI: mean (SD) | 27.42 (5.58) | 26.95 (4.81) | 26.08 (4.59) | F (2732) = 5.0 | P = 0.007 |
Moderate risk | 28.38 (5.88) | 26.69 (5.12) | 25. 14 (3.71) | ||
Average risk | 26.29 (4.39) | 26.76 (4.96) | 26.11 (4.96) | ||
Below average risk | 27.57 (5.95) | 26.95 (4.81) | 26.94 (4.82) | ||
Ethnicity: % (n)a,b | χ2 (10) = 11.8 | P = 0.30 | |||
White | 93.3% (253) | 90.9% (179) | 92.3% (274) | ||
Asian or Asian British | 0.7% (2) | 2.0% (4) | 1.0% (3) | ||
Black or Black British | 0% (0) | 1.5% (3) | 1.7% (5) | ||
Mixed | 1.1% (3) | 1.0% (2) | 0% (0) | ||
Other | 2.6% (7) | 2.5% (5) | 3.4% (10) | ||
Not indicated | 3.3% (6) | 3.0% (6) | 1.7% (5) | ||
IMD: mean (SD) | 5.31 (2.68) | 5.83 (3.02) | 6.31 (2.88) | F (2762) = 8.7 | P < 0.001 |
Moderate risk | 5.83 (2.45) | 6.07 (2.93) | 6.56 (3.08) | ||
Average risk | 5.65 (2.82) | 5.92 (3.02) | 6.69 (2.63) | ||
Below average risk | 4.67 (2.65) | 5.42 (3.13) | 5.67 (2.84) | ||
Number of relatives affected by breast cancer: % (n)a | χ2 (4) = 12.0 | P = 0.017 | |||
None | 87.5% (237) | 75.6% (149) | 80.8% (240) | ||
One | 11.8% (32) | 23.4% (46) | 18.9% (56) | ||
Two or more | 0.7% (2) | 1.0% (2) | 0.3% (1) | ||
Mammography: % (n)a | χ2 (2) = 285.5 | P < 0.001 | |||
First | 30.3% (82) | (160) | 93.9% (279) | ||
Repeat | 69.7% (189) | 18.8 % (37) | 6.1% (18) | ||
Location: % (n)a | χ2 (10) = 226.7 | P < 0.001 | |||
Trafford | 35.8% (97) | 26.4% (52) | 18.5% (55) | ||
Withington | 33.2% (90) | 8.6% (17) | 4.4% (13) | ||
Manchester city | 10.7% (29) | 7.6% (15) | 7.1% (21) | ||
Oldham | 11.1% (30) | 18.3% (36) | 14.1% (42) | ||
Salford | 9.2% (25) | 12.2% (24) | 10.4% (31) | ||
Tameside | 0% (0) | 26.9% (53) | 45.5% (135) | ||
Days from risk assessment to risk feedback: mean (SD) | 1124.5 (95.9) | 991.7 (80.9) | 838.2 (67.3) | F (2762) = 869.4 | P < 0.001 |
Moderate risk | 1161.7 (81.1) | 996.3 (84.6) | 801.0 (100.2) | ||
Average risk | 1068.8 (111.2) | 994.7 (82.4) | 853.3 (26.8) | ||
Below average risk | 1132.6 (77.7) | 982.7 (74.8) | 860.4 (28.4) | ||
