Fig. 2
From: Differential expression of IL-6/IL-6R and MAO-A regulates invasion/angiogenesis in breast cancer
Inhibitory effect in different targets. a Effect of IL-6R/IL-6R inhibition by Dia on MAO-A activity by western blot analysis. b Effect of IL-6/IL-6R inhibition by Dia treatment in hypoxic breast cancer cells on MAO-A activities. MAO-A expression was highly up-regulated due to inhibition of IL-6. c Cells were treated with CoCl2 and siRNA IL-6R transfection or Dia treatment was performed in hypoxic breast cancer cells. MAO-A and HIF-1α expression was shown. d Western blot using STAT3 inhibitor (PF-04965842) in dose dependent manner. e Western blot using AG126, a specific inhibitor of MAPK. f Western blot using LY294002, a specific PI3K/Akt inhibitor
