Fig. 2

Construction of the MASAN model. a Pipeline of feature selection. b Procedure for optimisation of the genetic algorithm. Eight features (dotted yellow line) with a C-index (blue line) of 0.67 were identified at 100 iterations. c Comparison of predictive performance of all combinations of eight features. The combinations with times of significant stratification >900 were displayed. Five features (MASAN) with an average C-index of 0.6514 and 993 significant stratifications were identified