Fig. 1 | British Journal of Cancer

Fig. 1

From: Safety, anti-tumour activity, and pharmacokinetics of fixed-dose SHR-1210, an anti-PD-1 antibody in advanced solid tumours: a dose-escalation, phase 1 study

Fig. 1

Antitumour activity of SHR-1210 in patients with advanced solid cancers. a The best change from baseline in the sum of the longest target lesion diameters per patient. b Duration of disease control. c Longitudinal change from baseline in the sum of the longest target lesion diameters. Responses were assessed in accordance with the RECIST v1.1 by independent review in all 36 patients. Colour code defines dose level of treatment with SHR-1210. Green, blue, purple bars represent dose levels 60 mg, 200 mg and 400 mg, respectively. The golden pentastar indicates patients with partial response. The red circle indicates patients with progressive disease at the first evaluation. The red triangle indicates patients with progressive disease after non-progressive disease. The black star represents the last dose of SHR-1210 patients receive. The black arrow indicates those patients who are still under treatment at the time of data collection

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