Table 3 Outcome in 42 patients with BRAF-mutant tumours: OS in subgroups defined by baseline level of CA 19-9 and IL-6

From: Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome

Variables

n

Events

Median OS (95% CI)

HR (95% CI)

CA 19-9 <35 kU/L IL-6 <5.6 ng/L

10

9

26.0 (15.2–36.8)

1

CA 19-9 ≥35 kU/L IL-6 <5.6 ng/L

7

7

11.8 (9.4–14.1)

4.3 (1.3–14.0)

CA 19-9 <35 kU/L IL-6 ≥5.6 ng/L

6

6

6.3 (5.2–7.4)

4.8 (1.5–14.9)

CA 19-9 ≥35 kU/L IL-6 ≥5.6 ng/L

19

19

8.1 (2.3–13.9)

9.0 (3.0–26.9)

  1. IL-6 interleukin-6, CA carbohydrate antigen, CI confidence interval, HR hazard ratio, OS overall survival
Back to article page