Fig. 1

Swim lanes illustrating the 26 patients on the trial. Blue bars represent time on abiraterone plus prednisone. Diamonds represent progression to abiraterone plus prednisone (biochemical in yellow, biochemical+radiological in brown) and starting date on AA+D (switch). Red bars represent time to biochemical progression after switch. Green bars represent time between biochemical progression and radiological or clinical progression-free survival. AA+P, abiraterone plus prednisone; bPFS, biochemical progression-free survival; rPFS, radiolographic progression-free survival; cPFS, clinical progression-free survival; PSA PD, biochemical progression; RX PD, radiological progression