Table 1 Adjusted HRs of colon and rectal cancer by different measures of adiposity in men and women

From: Adiposity and risks of colorectal and small intestine cancer in Chinese adults: a prospective study of 0.5 million people

Adiposity

Colon

Rectal

 

Men

Women

Men

Women

 

Mediana

No.b

HR (95% CI)c

Median

No.

HR (95% CI)

No.

HR (95% CI)

No.

HR (95% CI)

BMI

 <20.0

19.0

100

1.03 (0.84, 1.26)

18.9

90

0.88 (0.71, 1.08)

124

1.08 (0.90, 1.31)

87

0.87 (0.70, 1.07)

 20.0 to <22.5

21.3

173

1.00 (0.86, 1.16)

21.4

198

1.00 (0.87, 1.15)

201

1.00 (0.87, 1.15)

188

1.00 (0.87, 1.16)

 22.5 to <25.0

23.7

253

1.31 (1.16, 1.48)

23.7

233

0.94 (0.83, 1.07)

237

1.10 (0.97, 1.25)

230

0.99 (0.87, 1.13)

 25.0 to <27.5

26.0

188

1.32 (1.14, 1.53)

26.0

195

1.05 (0.91, 1.21)

191

1.23 (1.06, 1.42)

168

0.97 (0.83, 1.12)

 ≥27.5

28.8

136

1.69 (1.41, 2.01)

29.1

179

1.23 (1.05, 1.43)

134

1.49 (1.24, 1.77)

156

1.12 (0.95, 1.32)

1-SD increment d

  

1.18 (1.10, 1.26)

  

1.10 (1.03, 1.17)

 

1.11 (1.03, 1.19)

 

1.05 (0.98, 1.12)

WCe

 Quintile 1

69.8

131

1.02 (0.85, 1.22)

67.2

131

0.94 (0.79, 1.11)

157

0.98 (0.83, 1.15)

140

1.06 (0.90, 1.26)

 Quintile 2

76.0

113

1.00 (0.83, 1.21)

73.4

135

1.00 (0.84, 1.19)

143

1.00 (0.85, 1.18)

126

1.00 (0.84, 1.19)

 Quintile 3

81.5

145

1.21 (1.03, 1.42)

78.3

179

1.15 (1.00, 1.34)

167

1.15 (0.99, 1.33)

169

1.17 (1.01, 1.37)

 Quintile 4

87.2

212

1.66 (1.45, 1.90)

83.5

207

1.22 (1.06, 1.39)

175

1.15 (0.99, 1.34)

164

1.04 (0.89, 1.21)

 Quintile 5

95.0

249

1.86 (1.62, 2.12)

91.5

243

1.23 (1.08, 1.41)

245

1.52 (1.32, 1.74)

230

1.23 (1.07, 1.41)

1-SD increment d

  

1.28 (1.19, 1.37)

  

1.12 (1.04, 1.19)

 

1.18 (1.10, 1.27)

 

1.04 (0.97, 1.12)

WHRf

 Quintile 1

0.82

104

0.75 (0.61, 0.91)

0.78

155

1.22 (1.03, 1.43)

126

0.91 (0.76, 1.09)

107

0.78 (0.64, 0.94)

 Quintile 2

0.87

147

1.00 (0.85, 1.18)

0.83

134

1.00 (0.84, 1.19)

149

1.00 (0.85, 1.17)

150

1.00 (0.85, 1.18)

 Quintile 3

0.90

141

1.05 (0.89, 1.24)

0.86

131

1.10 (0.93, 1.30)

174

1.30 (1.12, 1.51)

129

0.95 (0.80, 1.12)

 Quintile 4

0.93

214

1.28 (1.12, 1.46)

0.89

192

1.24 (1.08, 1.43)

197

1.21 (1.05, 1.39)

202

1.11 (0.96, 1.27)

 Quintile 5

0.98

244

1.38 (1.21, 1.57)

0.95

283

1.39 (1.22, 1.57)

241

1.41 (1.24, 1.61)

241

0.96 (0.84, 1.10)

1-SD increment d

  

1.20 (1.14, 1.27)

  

1.07 (1.00, 1.14)

 

1.15 (1.09, 1.23)

 

1.05 (0.98, 1.12)

  1. BMI body mass index, WC waist circumference, WHR waist-to-hip ratio, ICD-10 colon C18, ICD-10 rectal C20.
  2. a Median of adiposity measures in each adiposity category.
  3. b Number of cases in each adiposity category.
  4. c Model was stratified by age-at-risk and region, and adjusted for age at baseline, education, smoking, alcohol, physical activity, fresh fruits, vegetables, red meat, and dairy products.
  5. d SD: 3.4 kg/m2 for BMI, 9.8 cm for WC, 0.07 for WHR.
  6. e Cut points (cm): men 73.1, 79.0, 84.3, 90.5; women 70.8, 76.0, 81.0, 87.0.
  7. f Cut points: men 0.85, 0.89, 0.92, 0.96; women 0.81, 0.85, 0.88, 0.92
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