Table 1 Demographic and clinical characteristics of TCGA and SEER cases

From: Characteristics of The Cancer Genome Atlas cases relative to U.S. general population cancer cases

Cancer types

Age

Male

Stage

Restricted mean survival months

I

II

III

IV

TCGAa N (mean, SD)

SEER N (mean, SD)

TCGA N (%)

SEER N (%)

TCGA N (%)

SEER N (%)

TCGA N (%)

SEER N (%)

TCGA N (%)

SEER N (%)

TCGA N (%)

SEER N (%)

TCGA N (mean, SD)

SEER N (mean, SD)

All cancers

11,109 (59.1, 14.4)

1,027,049 (63.0, 13.9)

ACC

92 (47.2, 16.3)

349 (52.5, 20.0)

32 (34.8)

131 (37.5)

9 (10.0)

15 (4.4)

44 (48.9)

103 (30.5)

19 (21.1)

48 (14.2)

18 (20.0)

172 (50.9)

79 (11.7, 1.3)

337 (8.9, 4.3)

BLCA

412 (68.1, 10.6)

49,593 (70.1, 12.1)

304 (73.8)

37,796 (76.2)

2 (0.5)

10,796 (51.9)

131 (32.0)

5353 (25.7)

141 (34.4)

1644 (7.9)

136 (33.2)

3005 (14.5)

391 (11.1, 2.3)

20,621 (10.4, 3.3)

BRCA

1096 (58.4, 13.2)

203,828 (60.7, 13.6)

12 (1.1)

1474 (0.7)

183 (17.1)

97,507 (49.5)

621 (57.9)

65,060 (33.0)

249 (23.1)

23,245 (11.8)

20 (1.9)

11,363 (5.8)

979 (11.9, 0.5)

195,859 (11.8, 1.5)

CESC

307 (48.3, 13.8)

11,454 (50.1, 14.7)

163 (54.3)

5343 (49.0)

70 (23.3)

1494 (13.7)

46 (15.3)

2471 (22.6)

21 (7.0)

1606 (14.7)

259 (11.6, 1.4)

10,799 (11.2, 2.5)

CHOL

45 (63.6, 12.2)

4743 (67.3, 13.2)

20 (44.4)

2363 (49.8)

20 (44.4)

569 (17.6)

11 (24.4)

541 (16.8)

4 (8.9)

270 (8.4)

10 (22.2)

1846 (57.2)

43 (10.6, 3.3)

3214 (7.0, 4.7)

COAD

459 (66.9, 13.1)

78,858 (66.7, 14.1)

243 (52.9)

38,938 (49.4)

76 (17.0)

17,127 (23.2)

178 (39.7)

20,294 (27.5)

129 (28.8)

19,987 (27.1)

65 (14.5)

16,464 (22.3)

268 (11.6, 1.7)

73,335 (10.5, 3.5)

DLBC

48 (55.3, 14.2)

20,129 (63.7, 16.7)

22 (45.8)

11,040 (54.9)

8 (19.1)

2937 (17.3)

17 (40.5)

3916 (23.1)

5 (11.9)

3497 (20.6)

12 (28.6)

6604 (39.0)

41 (11.9, 0.4)

16,804 (9.7, 4.1)

ESCA

185 (62.5, 11.9)

12,068 (66.3, 11.7)

158 (85.4)

9617 (79.7)

18 (11.1)

1934 (18.3)

79 (48.8)

1860 (17.6)

56 (34.6)

2927 (27.7)

9 (5.6)

3854 (36.4)

143 (10.8, 2.6)

10,429 (8.2, 4.4)

GBM

596 (57.8, 14.4)

9818 (62.1, 14.7)

366 (61.4)

5628 (57.3)

566 (9.1, 3.9)

9743 (7.7, 4.5)

HNSC

527 (60.9, 11.9)

36,907 (62.5, 12.2)

386 (73.1)

27,933 (75.7)

27 (6.0)

7330 (22.4)

74 (16.3)

3924 (12.0)

82 (18.1)

5589 (17.1)

270 (59.6)

15,873 (48.5)

437 (11.1, 2.4)

32,482 (10.8, 2.9)

KICH

113 (51.2, 13.9)

2151 (58.6, 13.9)

62 (54.9)

1185 (55.1)

54 (47.8)

1380 (65.6)

33 (29.2)

377 (17.9)

19 (16.8)

303 (14.4)

7 (6.2)

45 (2.1)

110 (11.9, 1.1)

2076 (11.9, 0.9)

KIRC

537 (60.6, 12.2)

22,371 (60.3, 12.4)

346 (64.4)

13,855 (61.9)

269 (50.4)

13,769 (62.7)

57 (10.7)

1913 (8.7)

125 (23.4)

3722 (17.0)

83 (15.5)

2550 (11.6)

522 (11.4, 2.1)

21,768 (11.5, 2.1)

KIRP

288 (61.5, 12.1)

4576 (61.3, 11.9)

214 (73.5)

3406 (74.4)

173 (66.3)

3249 (73.7)

21 (8.1)

449 (10.2)

52 (19.9)

447 (10.1)

15 (5.8)

266 (6.0)

244 (11.8, 0.9)

4362 (11.5, 2.1)

LAML

200 (55.0, 16.1)

11,671 (60.3, 21.7)

109 (54.5)

6336 (54.3)

173 (9.6, 3.6)

11,491 (7.0, 5.0)

LGG

515 (42.9, 13.4)

952 (35.4, 20.6)

285 (55.3)

536 (56.3)

500 (11.7, 1.4)

943 (11.4, 2.3)

LIHC

376 (59.5, 13.5)

22,642 (63.1, 11.0)

255 (67.6)

17,529 (77.4)

175 (49.6)

7604 (40.3)

87 (24.7)

3774 (20.0)

86 (24.4)

3520 (18.7)

5 (1.4)

3953 (21.0)

320 (11.1, 2.7)

18,716 (7.9, 4.8)

LUAD

503 (65.3, 10.0)

69,483 (67.4, 11.5)

242 (46.4)

33,003 (47.5)

279 (54.3)

15,333 (22.8)

124 (24.1)

5027 (7.5)

85 (16.5)

10,599 (15.8)

26 (5.1)

36,182 (53.9)

444 (11.3, 1.9)

66,875 (8.3, 4.6)

LUSC

495 (67.3, 8.6)

31,355 (69.7, 10.1)

373 (74.0)

19,553 (62.4)

245 (49.0)

6069 (20.3)

163 (32.6)

3803 (12.7)

85 (17.0)

8815 (29.5)

7 (1.4)

11173 (37.4)

381 (10.8, 2.7)

29,771 (7.9, 4.6)

MESO

87 (63.0, 9.8)

2561 (71.4, 12.3)

71 (81.6)

1928 (75.3)

10 (11.5)

437 (21.7)

16 (18.4)

221 (11.0)

45 (51.7)

466 (23.1)

16 (18.4)

892 (44.3)

85 (10.2, 3.1)

2011 (7.5, 4.5)

OV

587 (59.7, 11.5)

5126 (62.7, 12.6)

6 (1.1)

456 (9.1)

30 (5.3)

400 (8.0)

446 (78.1)

2669 (53.2)

89 (15.6)

1495 (29.8)

543 (11.3, 2.5)

5003 (10.9, 3.0)

PAAD

185 (64.9, 11.1)

29,367 (67.2, 12.1)

102 (55.1)

15,141 (51.7)

21 (11.5)

2587 (9.3)

152 (83.5)

8036 (28.7)

4 (2.2)

2708 (9.7)

5 (2.8)

14,629 (52.3)

173 (10.3, 2.9)

27,851 (6.8, 4.7)

PCPG

179 (47.3, 15.1)

176 (50.2, 18.9)

78 (43.6)

91 (51.7)

175 (11.9, 1.0)

166 (11.3, 2.5)

PRAD

500 (61.0, 6.8)

195,005 (65.7, 9.1)

156 (12.0, 0.0)

186,537 (11.8, 1.1)

READ

170 (64.5, 11.9)

26,251 (61.5, 13.5)

92 (54.1)

15,357 (58.5)

33 (20.5)

7346 (32.7)

51 (31.7)

4705 (21.0)

52 (32.3)

6335 (28.2)

25 (15.5)

4065 (18.1)

80 (11.9, 0.2)

22,242 (11.1, 2.6)

SARC

261 (60.9, 14.7)

3256 (59.3, 20.4)

119 (45.6)

1734 (53.3)

252 (11.6, 1.7)

3158 (9.2, 4.4)

SKCM

462 (58.2, 15.7)

61,799 (59.9, 16.3)

290 (61.7)

34,964 (56.6)

91 (21.4)

43,082 (76.2)

140 (32.9)

6950 (12.3)

171 (40.2)

4321 (7.6)

23 (5.4)

2205 (3.9)

405 (11.8, 0.9)

53,395 (11.7, 1.7)

STAD

438 (65.7, 10.8)

18,809 (66.2, 14.3)

285 (64.3)

11,540 (61.4)

59 (14.2)

3631 (22.2)

130 (31.3)

2552 (15.6)

183 (44.0)

3624 (22.2)

44 (10.6)

6536 (40.0)

340 (10.8, 2.4)

16,226 (8.4, 4.5)

TGCT

134 (32.0, 9.3)

8966 (34.4, 11.8)

101 (79.5)

6145 (72.2)

12 (9.5)

1170 (13.7)

14 (11.0)

1201 (14.1)

122 (11.9, 1.0)

8170 (11.9, 1.1)

THCA

507 (47.3, 15.8)

43,969 (49.1, 15.3)

136 (26.8)

10,040 (22.8)

285 (56.4)

30,698 (72.1)

52 (10.3)

3162 (7.4)

113 (22.4)

5387 (12.7)

55 (10.9)

3333 (7.8)

412 (12.0, 0.4)

41,825 (11.8, 1.2)

THYM

123 (58.2, 13.0)

584 (58.2, 14.1)

64 (51.6)

268 (45.9)

121 (11.9, 0.7)

575 (11.5, 1.9)

UCEC

545 (63.9, 11.1)

36,753 (61.5, 11.8)

342 (62.4)

27,851 (78.8)

52 (9.5)

1657 (4.7)

124 (22.6)

3795 (10.7)

30 (5.5)

2048 (5.8)

514 (11.8, 1.1)

35,073 (11.6, 1.7)

UCS

57 (69.7, 9.3)

164 (65.4, 11.1)

22 (38.6)

20 (13.3)

5 (8.8)

11 (7.3)

20 (35.1)

47 (31.3)

10 (17.5)

72 (48.0)

55 (10.8, 2.8)

138 (9.1, 4.)

UVM

80 (61.7, 13.9)

1315 (60.2, 14.7)

45 (56.3)

681 (51.8)

0

308 (33.2)

39 (49.4)

463 (50.0)

36 (45.6)

134 (14.5)

4 (5.1)

22 (2.4)

54 (11.6, 1.7)

911 (11.8, 1.1)

  1. ACC adrenocortical carcinoma, BLCA bladder urothelial carcinoma, BRCA breast invasive carcinoma, CESC cervical squamous cell carcinoma and endocervical adenocarcinoma, CHOL cholangiocarcinoma, COAD colon adenocarcinoma, DLBC lymphoid neoplasm diffuse large B-cell lymphoma, ESCA oesophageal carcinoma, GBM glioblastoma multiforme, HNSC head and neck squamous cell carcinoma, KICH kidney chromophobe, KIRC kidney renal clear cell carcinoma, KIRP kidney renal papillary cell carcinoma, LAML acute myeloid leukaemia, LGG brain lower grade glioma, LIHC liver hepatocellular carcinoma, LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma, MESO mesothelioma, OV ovarian serous cystadenocarcinoma, PAAD pancreatic adenocarcinoma, PCPG pheochromocytoma and paraganglioma, PRAD prostate adenocarcinoma, READ rectum adenocarcinoma, SARC sarcoma, SKCM skin cutaneous melanoma, STAD stomach adenocarcinoma, TGCT testicular germ cell tumours, THCA thyroid carcinoma, THYM thymoma, UCEC uterine corpus endometrial carcinoma, UCS uterine carcinosarcoma, UVM uveal melanoma, SD standard deviation.
  2. aAll cancer types have no missing values for age in TCGA except for BRCA (one case missing), HNSC (one case missing), KIRP (three cases missing), LIHC (one case missing), LUAD (nineteen cases missing), LUSC (nine cases missing), SKCM (eight cases missing), STAD (five cases missing), THYM (one case missing), and UCEC (three cases missing)