Fig. 1 | British Journal of Cancer

Fig. 1

From: Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy

Fig. 1

Prognostic role of CD8 and PD-L1 expressions in a control cohort of metastatic NSCLC using IHC. a Box plots showing the CD8 IHC expression respectively for patients with high (Sp142+) or low (Sp142−) expression of Sp142 labeling. b, c Kaplan–Meier estimates for overall survival; patients were stratified according to the CD8 (b), and Sp142 (c) labeling expressions: high expression (CD8+/Sp142+; in red) and low expression (CD8−/Sp142−; in blue). d Kaplan–Meier estimates for overall survival; patients were stratified in two groups: a group with low expression of CD8 labeling (CD8−) and high expression of Sp142 labeling (Sp142+) and a group with the other patients. Cutoffs for low and high expressions were defined with the Cutoff Finder method. *p < 0.05; **p < 0.01; ***p < 0.001; ****: p < 0.0001; ns not significant

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