Fig. 1

Analysis of mRNA expression in OV-KLK4–7 versus control OV-VC cells via PCR array and qPCR. Selected genes identified as being deregulated in OV-KLK4–7 (red columns) versus OV-VC (blue columns) cells in the PCR array were validated by qPCR using independently isolated RNA. OV-KLK4–7 cells displayed significant upregulation of MSN (a), KRT19 (b), COL5A2 (c), COL1A2 (d), BMP5 (e) and F10 (f) as well as downregulation of KRT7 (g), JUNB (h), BMP4 (j) and MMP1 (k) compared to OV-VC cells (*P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001)