Fig. 3 | British Journal of Cancer

Fig. 3

From: Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer

Fig. 3

Visualisation of differential protein expression of MSN, KRT19, KRT7 and JUNB in OV-KLK4–7 versus control OV-VC cells and tumour xenograft tissues by immunofluorescence and immunohistochemistry. (a) An increased staining of MSN and KRT19 and a decreased staining of KRT7 and JUNB was observed in OV-KLK4–7 compared to OV-VC cells. MSN was cell membrane-associated, while JUNB was located in the nucleus. KRT19 and KRT7 showed a cytoplasmic staining pattern, with a perinuclear staining for KRT7 (scale bars, 25 µm). (b) In accordance with the immunofluorescence results, MSN and KRT19 showed increased and KRT7 and JUNB decreased immunohistochemical staining in OV-KLK4–7-derived tumour compared to OV-VC-derived tumour tissues (scale bars, 100 µm; insets: scale bars, 25 µm)

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