Table 2 Association between KLK4–7, MSN and KRT19 expression in advanced high-grade serous ovarian cancer patients (FIGO III/IV)

From: Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer

 

Number of patients

MSN

KRT19

  

Low/high

Low/high

Total number of patients

66

31/35

29/37

KLK4

 

P = 0.245

P = 0.010

Low

27

15/12

17/10

High

39

16/23

12/27

KLK5

 

P = 0.782

P = 0.030

Low

31

14/17

18/13

High

35

17/18

11/24

KLK6

 

P = 0.056

P = 0.075

Low

24

15/9

14/10

High

42

16/26

15/27

KLK7

 

P = 0.001

P = 0.684

Low

30

21/9

14/16

High

36

10/26

15/21

  1. All parameters were dichotomised into low and high levels by the median, immuno-reactive score (IRSKLK4: 6.6; IRSKLK5: 5.0; IRSKLK6: 3.5; IRSKLK7: 4.5; IRSMSN: 4.6; IRSKRT19: 7.5). Associations between the parameters were evaluated using the χ2 test. P-values considered statistically significant (P ≤ 0.05) are indicated in bold, trends towards significance in italics
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