British Journal of Cancer

Table 1 Associations between CD20-status and clinicopathological parameters in the discovery cohort, validation cohort and KIRC

From: A minority-group of renal cell cancer patients with high infiltration of CD20+B-cells is associated with poor prognosis

	Discovery cohort				Validation cohort				KIRC
	Total (n=297)	CD20		p-value	Total (n=64)	CD20		p-value	Total (n=534)	MS4A1/CD19/PAX5		p-value
	Total (n=297)	Low (n=256)	High (n=41)	p-value	Total (n=64)	Low (n=46)	High (n=18)	p-value	Total (n=534)	Low (n=477)	High (n=57)	p-value
Sex
Female	127	112	15	0.39^a	14	10	4	1.0^b	188	163	25	0.15^a
Male	170	144	26		50	36	14		345	313	32
Missing	0	0	0		0	0	0		2	2	0
Age
<60	100	86	14	0.98^a	13	8	5	0.49^b	265	238	27	0.71^a
≥60	194	167	27		51	38	13		268	238	30
Missing	3	3	0		0	0	0		1	1	0
Histology
Clear cell	238	206	32	0.37^b	59	42	17	0.81^a
Papillary	11	10	1		3	2	1
Sarcomatoid	7	7	0		0	0	0
Chromophobic	3	1	2		1	1	0
Missing	38	32	6		1	1	0
T-stage
1	32	26	6	0.16^b	10	7	3	0.82^a	273	255	18	0.002^a*
2	39	33	6		14	11	3		69	60	9
3	34	33	1		38	26	12		180	152	28
4	62	50	12		1	1	0		11	9	2
Missing	130	114	16		1	1	0		1	1	0
Fuhrman grade
1	112	103	9	0.007^b*
2	107	92	15
3	54	39	15
4	21	19	2
Missing	3	3	0
MSKCC
Low					26	20	6	0.85^a
Intermidiate					31	22	9
High					3	2	1
Missing					4	2	2
N-stage
0									239	215	24	0.084^b
1									16	12	4
Missing									279	250	29
M-stage
0	239	211	28	0.034^a*	40	29	11	1.0^b	421	381	40	0.031^a*
1	58	45	13		24	17	7		79	65	14
Missing	0	0	0		0	0	0		34	31	3

^aPearson Chi-square test
^bFisher exact test
^*P-value < 0.05 is considered significant

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