Table 2 Classification of misleading reporting strategies used by authors when presenting prognostic factor studies in oncology, and frequency of each strategy in a sample of 98 prognostic factor studies published in oncology journals with an impact factor of seven or greater

From: Overinterpretation and misreporting of prognostic factor studies in oncology: a systematic review

Misleading reporting strategy

Places within a prognostic factor oncology study report where this strategy can occur

Test to check whether this strategy was used

Number of studies using this strategy

Main text

Abstract

Selective reporting

Difference between the numbers of outcomes and prognostic factors pre-specified in Methods section and reported in Results section

The prognostic factor effect for a specific outcome or a specific prognostic factor is missing

35

34

Difference between the numbers of subgroup and subpopulation criteria pre-specified in Methods section and reported in Results section

The prognostic factor effect for a specific subgroup or a subpopulation is missing

5

Not assessed

Inconsistent use of statistics across all prognostic factor–outcome associations, when more than one prognostic factor effects are assessed

Some PF effects are reported within a multivariable model, whereas others are reported within a univariate analysis

24

41

Incomplete reporting of subgroup analysis results for the prognostic factor effect

For any subgroup analysis reported, whether pre-specified or not, an interaction test p value is not reported

35 (out of 90 studies assessing more than one prognostic factor effect)

42 (out of 90 studies assessing more than one prognostic factor effect)

Incomplete reporting

Incomplete reporting of the main analysis results for the prognostic factor effect

Only adjusted hazard ratios are reported for the prognostic factor effect, not 95% confidence intervals or p values; OR Only a p value is reported for the prognostic factor effect, not adjusted hazard ratios; OR No statistical results are reported

24

41

Incomplete reporting of subgroup analysis results for the prognostic factor effect

For any subgroup analysis reported, whether pre-specified or not, an interaction test p value is not reported

29 (out of 51 studies reporting a subgroup analysis in the main text)

23 (out of 28 studies reporting a subgroup analysis in the abstract)

  1. Of the 57 abstracts presenting unadjusted prognostic factor effects, 23 reported were related to non-significant findings after adjustment in the full text