Table 3 Toxicity according to CDA activity (number of patients)
Low activity ≤7.2 U/mg (61 pts) | High activity > 7.2 U/mg (60 pts) | |
|---|---|---|
Grade 3–4 (%) | Grade 3–4 (%) | |
Haematological (all events) | 18 (29.5) | 13 (22) |
Anaemia | 6 (9.8) | 5 (8.3) |
Neutropenia | 20 (32) | 16 (26.6) |
Thrombocytopenia | 9 (14.7) | 7 (11.6) |
Non-haematological (all events) | 10 (16) | 10 (17) |
Vomiting | 4 (6.5) | 3 (5) |
Nausea | 3 (4.9) | 4 (6.6) |
Weakness | 3 (4.9) | 3 (5) |
Paraesthesia | 0 | 0 |
Tinnitus | 0 | 0 |
Hepatic toxicity | 0 | 0 |
Renal toxicity | 0 | 0 |
