Fig. 3 | British Journal of Cancer

Fig. 3

From: Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts

Fig. 3

Indels generated during long-term niraparib treatment. a, b The mean number of short insertions (a) or short deletions (b) generated per sequenced genome in each indicated cell line following mock treatment or treatment with the indicated concentration of niraparib. Red symbols show the values for individual samples. c A classification of detected short deletion events by sequence context. The minimum length of classified microhomologies was 1 bp. Error bars indicate SEM in all panels. Significant differences are indicated (p < 0.05, unpaired t test)

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