Fig. 1 | British Journal of Cancer

Fig. 1

From: WT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer

Fig. 1

WT1 is expressed in human breast cancer and in healthy control tissue. Double immunofluorescence showing a healthy breast tissue displaying no endothelial WT1 expression in a small capillary. b Healthy breast tissue exhibiting clear expression of WT1 in endothelial (red) (denoted by broken white arrow) and smooth muscle cells (red) (denoted by white arrow) in the arterial wall. c Breast cancer (Grade II, ER-positive, HER2-negative) sample displaying WT1+ (red) endothelial cells (CD31+; green) in both the artery and small capillaries; with WT1-positive smooth muscle cells evident in the arterial media. d Breast cancer (Grade III, ER-positive, HER2-positive) sample exhibiting WT1+ (red) ducts, arteries and tumour stromal cells. Wt1 (red), CD31 (green), DAPI (blue). Scale bars represent 50 µm

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