Fig. 2
The tumour microenvironment and mutational landscape across tumour types. Heatmap representing the average number of somatic mutations (ranging from 0.7 per megabase in thyroid cancer, to 11 per megabase in melanoma)155 and relative abundance of infiltrating immune and stromal cells across 15 different human tumours as determined by Microenvironment Cell Populations-counter (MCP-counter).156 The cancer types are organised from left to right according to the abundance of T cell infiltrate. SqCC, squamous cell carcinoma; Adeno, adenocarcinoma; H&N, head and neck; ccRCC, clear cell renal cell carcinoma; LG, low-grade; HG, high-grade; PTC, papillary thyroid cancer
