Fig. 4 | British Journal of Cancer

Fig. 4

From: (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations

Fig. 4

(P)RR silencing inhibits proliferation and induces apoptosis of CRC cells in vitro. a, b Cell number counting of DLD-1 (a) and HCT116 (b) cells during 72 h after siRNA transfection (n = 4). N.S.: not significant, **P < 0.01, ***P < 0.001 vs. scrambled siRNA group. c, d Proliferative activity of DLD-1 (c) and HCT116 (d) cells measured by WST-1 assay at 72 h after siRNA transfection (n = 6). Data are expressed as relative ratios to vehicle (without siRNA transfection) group. N.S.: no significant difference, *P < 0.05. e, f Flow cytometry detection of apoptosis and cell cycle distribution of DLD-1 (e) and HCT116 (f) cells at 72 h after siRNA transfection. Numerical data are presented as mean ± SEM

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