Table 1 Baseline characteristics of study participants (n (%) or median (range)): results from the NHS and NHSII
Cases | Controls | |
|---|---|---|
n = 337 | n = 337 | |
Age at blood collection, years | 60 (34 to 81) | 60 (35 to 80) |
Menopausal status at blood collection | ||
Premenopausal | 77 (23) | 76 (23) |
Postmenopausal | 232 (69) | 232 (69) |
Perimenopausal/unknown | 28 (9) | 29 (9) |
Parity | ||
Nulliparous | 56 (17) | 28 (8) |
1 | 25 (7) | 16 (5) |
2 | 109 (32) | 103 (31) |
3 | 74 (22) | 91 (27) |
4+ | 73 (22) | 99 (29) |
OC use | ||
Never | 158 (47) | 160 (47) |
<1 year | 43 (13) | 39 (12) |
1–5 years | 81 (24) | 63 (19) |
5+ years | 55 (16) | 75 (22) |
Reported tubal ligation | 53 (16) | 74 (22) |
Marital status | ||
Never married | 10 (3) | 4 (1) |
Married/living with partner | 268 (79) | 273 (81) |
Divorced/separated | 20 (6) | 26 (8) |
Widowed | 39 (12) | 34 (10) |
Weight change between age 18 years and blood collection, kg | 11 (−30 to 91) | 9 (−17 to 61) |
Case characteristics | ||
|---|---|---|
Time between blood collection and diagnosis, years | 7 (<1 to 25) | |
Age at diagnosis, years | 68 (37 to 89) | |
Borderline ovarian tumours | 80 (24) | |
Invasive epithelial ovarian cancer | 257 (76) | |
Serous | 170 (66) | |
Non-serousa | 53 (21) | |
Rapidly fatalb | 94 (37) | |
Less aggressive diseaseb | 144 (56) | |
