Table 2 Quality of life scales at baseline according to treatment assignment
Quality of life scales | Continuous letrozole (n = 455) | Intermittent letrozole (n = 500) | Continuous letrozole (n = 455) | Intermittent letrozole (n = 500) | ||||
|---|---|---|---|---|---|---|---|---|
Original score rangea | Transformed score rangeb | |||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
BCPT symptom scalesa | ||||||||
Hot flushes | 1.1 | 1.0 | 1.1 | 1.1 | 71.8 | 24.6 | 71.5 | 27.0 |
Nausea | 0.1 | 0.3 | 0.1 | 0.4 | 97.0 | 8.5 | 96.4 | 10.2 |
Bladder control | 0.5 | 0.8 | 0.5 | 0.7 | 86.8 | 19.0 | 86.5 | 18.1 |
Vaginal problems | 1.2 | 1.2 | 1.1 | 1.2 | 69.2 | 31.1 | 71.8 | 30.4 |
Musculoskeletal pain | 1.2 | 0.9 | 1.3 | 1.0 | 69.8 | 23.0 | 68.6 | 24.0 |
Cognitive problems | 1.0 | 0.9 | 1.0 | 0.9 | 74.3 | 21.6 | 75.1 | 22.5 |
Weight problems | 1.0 | 1.0 | 0.9 | 1.0 | 74.7 | 24.6 | 76.8 | 24.7 |
Arm problems | 0.6 | 0.8 | 0.6 | 0.8 | 85.6 | 19.5 | 85.1 | 19.9 |
LASA symptom scales | ||||||||
Hot flushes | 69.1 | 28.4 | 68.6 | 30.4 | ||||
Sleep disturbance | – | – | – | – | 68.0 | 26.6 | 67.7 | 28.9 |
Tiredness | – | – | – | – | 62.6 | 27.6 | 63.7 | 26.4 |
Difficulties in becoming aroused | – | – | – | – | 64.2 | 30.1 | 66.7 | 29.7 |
Loss of sexual interest | – | – | – | – | 54.3 | 33.4 | 55.9 | 34.2 |
LASA global scales | ||||||||
Physical well-being | – | – | – | – | 78.2 | 20.7 | 77.6 | 22.2 |
Mood | – | – | – | – | 78.0 | 22.0 | 76.8 | 23.2 |
Coping effort | – | – | – | – | 79.0 | 23.6 | 76.8 | 81.3 |
Treatment burden | – | – | – | – | 77.5 | 23.5 | 77.4 | 23.4 |
