Table 4 Multidisciplinary team (MDT) decision-making for adjuvant therapy
MDT decision-making per patient | All patients (n = 2540) | Mastectomy only (n = 1532) | Implant (n = 675) | Pedicled flap (n = 105) | Free-flap (n = 228) | P-value |
|---|---|---|---|---|---|---|
Chemotherapy | ||||||
Recommended by MDT | 649 (25.6) | 421 (27.5) | 154 (22.8) | 28 (26.7) | 46 (20.2) | <0.001 |
For discussion with patient | 188 (7.4) | 138 (9.0) | 36 (5.3) | 5 (4.8) | 9 (3.9) | |
For oncotype DX testing | 181 (7.1) | 95 (6.2) | 64 (9.5) | 5 (4.8) | 17 (7.5) | |
Not recommended by MDT | 1509 (59.4) | 872 (56.9) | 415 (61.5) | 67 (63.8) | 155 (68.0) | |
Not reported | 13 (0.5) | 6 (0.4) | 6 (0.9) | 0 (0.0) | 1 (0.4) | |
Radiotherapy | ||||||
Recommended by MDT | 909 (35.7) | 614 (40.1) | 198 (29.3) | 35 (33.3) | 62 (27.2) | <0.001 |
For discussion with patient | 125 (4.9) | 86 (5.6) | 19 (2.8) | 1 (1.0) | 19 (8.3) | |
Not recommended by MDT | 1492 (58.7) | 828 (54.0) | 449 (66.5) | 69 (65.7) | 146 (64.0) | |
Not reported | 14 (0.5) | 4 (0.3) | 9 (1.3) | 0 (0.0) | 1 (0.4) | |
Patient accepts adjuvant treatment (either chemotherapy or radiotherapy or both) | 1235 (48.6) | 804 (52.5) | 288 (42.7) | 50 (47.6) | 93 (40.8) | <0.001 |
Time from last oncological procedure to first adjuvant treatment (days) median (IQR) (n = 1131) | 53 (41–65) | 52 (41–66) | 51 (41–63) | 57 (42–73) | 57 (46–72) | 0.026 |
Chemotherapy as 1st adjuvant treatment | 627 (55.4) | 409 (55.4) | 147 (56.5) | 25 (52.1) | 46 (54.1) | 0.939 |
Time from last oncological procedure to 1st chemotherapy (days) median (IQR) | 47 (37–59) | 47 (37–59) | 46 (35–57) | 46 (39–58) | 57 (41–70) | 0.063 |
Reported delays of >90 days of planned chemotherapy (n = 637) | 31 (4.9) | 21 (5.1) | 4 (2.7) | 3 (11.5) | 3 (6.5) | 0.228 |
Radiotherapy as 1st adjuvant treatment | 504 (44.6) | 329 (44.6) | 113 (43.5) | 23 (47.9) | 39 (45.9) | 0.939 |
Time from last oncological procedure to 1st radiotherapy (days) median (IQR) | 60 (48–73) | 59 (48–73) | 60 (45–68) | 63 (53–85) | 62 (50–76) | 0.248 |
Reported delays of >56 days (8 weeks) of planned radiotherapy (n = 616) | 389 (63.2) | 258 (62.8) | 83 (61.9) | 23 (79.3) | 25 (59.5) | 0.308 |
