Table 1 Inter-assay agreement evaluated by Cohen’s κ coefficient in defining the presence of a PD-L1-positive TIC and NTIC in patients with hepatocellular carcinoma (n = 100)

From: Clinical implications of heterogeneity in PD-L1 immunohistochemical detection in hepatocellular carcinoma: the Blueprint-HCC study

 

E1L3N

22c3

28-8

SP263

SP142

PD-L1+ TIC

 E1L3N

–

0.211

0.175

0.235

0.209

 22c3

0.222

–

0.313

0.396

0.222

 28-8

0.175

0.313

–

0.257

0.199

 SP263

0.235

0.263

0.257

–

0.267

 SP142

0.209

0.222

0.199

0.267

–

PD-L1+ NTIC

 E1L3N

–

0.038

0.061

0.036

0.030

 22c3

0.038

–

0.169

0.505

0.086

 28-8

0.061

0.169

–

0.111

0.004

 SP263

0.036

0.505

0.

–

0.041

 SP142

0.030

0.086

0.004

0.41

–

  1. TIC immune infiltrate in tumour, NTIC immune infiltrate in cirrhosis
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