Fig. 2 | British Journal of Cancer

Fig. 2

From: Enhanced antitumor effect of binimetinib in combination with capecitabine for biliary tract cancer patients with mutations in the RAS/RAF/MEK/ERK pathway: phase Ib study

Fig. 2

The efficacy of the combination of binimetinib and capecitabine. a Waterfall plot of tumour shrinkage, b progression-free survival and overall survival are present. Patients with mutant type on RAS/RAF/MEK/ERK exhibit better results in c waterfall plot, d progression-free survival, e swimmer plot of treatment duration and f overall survival compared with those with wild type. PD progressive disease, SD stable disease, PR partial response, PFS progression-free survival, OS overall survival, CI confidence interval, NR not reached

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