Table 2 Common ( ≥ 10%) adverse events (n = 34)
Variables, n (%) | All grades | Grade 3 | Grade 4 |
|---|---|---|---|
Stomatitis | 21 (61.7) | 1 (2.9) | 0 (0.0) |
Oedema | 17 (50.0) | 0 (0.0) | 0 (0.0) |
Nausea | 14 (41.2) | 1 (2.9) | 0 (0.0) |
Papulopustular rash | 14 (41.2) | 0 (0.0) | 0 (0.0) |
Palmar–plantar erythrodysesthesia syndrome | 14 (41.2) | 0 (0.0) | 0 (0.0) |
Fatigue | 14 (41.2) | 2 (5.9) | 0 (0.0) |
Fever | 10 (29.4) | 1 (2.9) | 0 (0.0) |
Pruritus | 9 (26.5) | 0 (0.0) | 0 (0.0) |
Anorexia | 9 (26.5) | 0 (0.0) | 0 (0.0) |
Abdominal pain | 8 (23.5) | 3 (8.8) | 0 (0.0) |
Diarrhoea | 8 (23.5) | 0 (0.0) | 0 (0.0) |
Vomiting | 7 (20.6) | 0 (0.0) | 0 (0.0) |
Dyspnoea | 7 (20.6) | 1 (2.9) | 0 (0.0) |
Anaemia | 5 (14.7) | 4 (11.8) | 0 (0.0) |
Cholangitis | 5 (14.7) | 4 (11.8) | 0 (0.0) |
Upper respiratory infection | 5 (14.7) | 0 (0.0) | 0 (0.0) |
Blood bilirubin increased | 5 (14.7) | 2 (5.9) | 0 (0.0) |
Back pain | 5 (14.7) | 0 (0.0) | 0 ((0.0) |
Neutrophil count decreased | 4 (11.8) | 1 (2.9) | 0 (0.0) |
Productive sputum | 4 (11.8) | 0 (0.0) | 0 (0.0) |
