Fig. 6

CPT sensitized HCC xenografts to EPI treatment. Nude mice were injected with SMMC-7721 cells. CPT, Camptothecin; EPI, epirubicin. Mice were treated with CPT, EPI or in combination (COM) twice a week for a total of three times. At the end of the experiments, tumours were excised and weighed at the end of the experiment. a Tumour growth curves for SMMC-7721 xenografts. b Representative images of excised tumours. c Excised xenograft tumours weights at the end of the experiment. n = 8–10; *p < 0.05 vs. Veh control. #p < 0.05 vs EPI