Fig. 1
From: Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel

Graphical schematic illustrating the algorithm for calculating dysregulation scores. For controls, baseline expression is calculated as the mean of the earliest up to three samples more than 2 years tDx. Deviation from that baseline is then used to score biomarker dysregulation either by up- or down-regulation based on specificity thresholds calculated from the controls